Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291948 | 0.85 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL197123 | 0.76 | TSHR (0.39) | TSHRLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL2586783 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL30030347 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL1315674 | 0.74 | ACHE (0.39) | TSHRLMNACYP2A6ALDH1A1NPC1 | |
| SCHEMBL8372962 | 0.74 | TSHR (0.50) | TSHRLMNACYP2A6PNMTALDH1A1 | |
| SCHEMBL1225074 | 0.74 | TSHR (0.50) | TSHRLMNACYP2A6PNMTALDH1A1 | |
| SCHEMBL28418551 | 0.73 | TSHR (0.37) | TSHRLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL704206 | 0.73 | ESR1 (0.40) | TSHRLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL7081177 | 0.71 | TSHR (0.37) | TSHRLMNACYP2A6PNMTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475020-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | FUJIFILM Corporation (JP) | 2012-07-11 | — | — | EP | disclosed |
| US-20120153817-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |