Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9932906 | 1.00 | S100A4 (0.40) | S100A4PTPRCALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9935445 | 0.85 | S100A4 (0.41) | S100A4PTPRCALDH1A1HTTTDP1 | |
| SCHEMBL7943962 | 0.83 | S100A4 (0.43) | S100A4PTPRCALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9934235 | 0.80 | UGCG (0.39) | PTPRCALDH1A1SMN1; SMN2TNFMAPT | |
| SCHEMBL9935368 | 0.80 | UGCG (0.39) | PTPRCALDH1A1SMN1; SMN2TNFMAPT | |
| SCHEMBL9933768 | 0.78 | IDH1 (0.45) | S100A4ALDH1A1HTTRECQLMAPT | |
| SCHEMBL13258582 | 0.75 | NPC1 (0.41) | ALDH1A1SMN1; SMN2TNFMAPTKMT2A | |
| SCHEMBL869069 | 0.74 | CYP1A2 (0.42) | S100A4PTPRCALDH1A1HTTRECQL | |
| SCHEMBL22291973 | 0.74 | ALDH1A1 (0.39) | S100A4PTPRCALDH1A1RECQLMAPT | |
| SCHEMBL6233523 | 0.74 | NPC1 (0.41) | ALDH1A1SMN1; SMN2TNFMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157494-A1 | ISOINDOLYL COMPOUNDS | HARRIS III RALPH NEW (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157494-A1 | ISOINDOLYL COMPOUNDS | P2RX7, P2RX3, P2RX1 | S100A4 1340/4885PTPRC 827/4885ALDH1A1 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.