SCHEMBL9936082

SCHEMBL9936082

CC(=O)C(C)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2650393 0.74
SCHEMBL810675 0.74
SCHEMBL1373127 0.73 LMNA (0.31) GAALMNAALDH1A1TSHR
SCHEMBL16218313 0.73 LMNA (0.31) GAALMNAALDH1A1TSHR
SCHEMBL105343 0.73 ALDH1A1 (0.44) GAAMEN1KMT2AHSD17B10ALDH1A1
SCHEMBL421936 0.73 MEN1 (0.31) GAAMEN1KMT2AHSD17B10ALDH1A1
SCHEMBL8160280 0.72
SCHEMBL5858699 0.71 PDK1 (0.39) ALDH1A1TSHR
SCHEMBL938172 0.71 MEN1 (0.31) GAAMEN1KMT2AHSD17B10
SCHEMBL10870961 0.71 ALDH1A1 (0.42) GAAMEN1KMT2AHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8709303-B2 Dielectric insulation medium ABB RESEARCH LTD. (CH) 2014-04-29 US claimed
EP-2652752-A1 DIELECTRIC INSULATION MEDIUM ABB Technology AG (CH) 2013-10-23 EP claimed
EP-2652753-A1 DIELECTRIC INSULATION MEDIUM ABB Technology AG (CH) 2013-10-23 EP claimed
EP-2652751-A1 DIELECTRIC INSULATION MEDIUM ABB Research Ltd. (CH) 2013-10-23 EP claimed
US-20130265692-A1 Dielectric Insulation Medium ABB RESEARCH LTD. (CH) 2013-10-10 US claimed
US-20130221292-A1 Dielectric Insulation Medium ABB TECHNOLOGY AG (CH) 2013-08-29 US claimed
WO-2012080246-A1 DIELECTRIC INSULATION MEDIUM ABB TECHNOLOGY AG (CH) 2012-06-21 WO claimed
WO-2012080269-A1 DIELECTRIC INSULATION MEDIUM ABB TECHNOLOGY AG (CH) 2012-06-21 WO claimed
WO-2012080222-A1 DIELECTRIC INSULATION MEDIUM ABB RESEARCH LTD (CH) 2012-06-21 WO claimed
EP-3230987-A1 APPARATUS FOR THE GENERATION, DISTRIBUTION AND/OR USAGE OF ELECTRICAL ENERGY AND COMPONENT FOR SUCH AN APPARATUS ABB Technology AG (CH) 2017-10-18 EP disclosed
EP-3167464-A1 ELECTRICAL DEVICE COMPRISING A GAS-INSULATED APPARATUS, IN PARTICULAR A GAS-INSULATED TRANSFORMER OR REACTOR ABB Schweiz AG (CH) 2017-05-17 EP disclosed
EP-3069421-A1 WATER AND CONTAMINATION ABSORBER FOR C02 INSULATED ELECTRICAL APPARATUS FOR THE GENERATION, TRANSMISSION, DISTRIBUTION AND/OR USAGE OF ELECTRICAL ENERGY ABB Technology AG (CH) 2016-09-21 EP disclosed
EP-2904617-A1 APPARATUS CONTAINING A DIELECTRIC INSULATION GAS COMPRISING AN ORGANOFLUORINE COMPOUND ABB Technology AG (CH) 2015-08-12 EP disclosed
WO-2014187940-A1 ELECTRICAL APPARATUS COMPRISING A CONTAMINATION-REDUCING COMPONENT ABB TECHNOLOGY AG (CH) 2014-11-27 WO disclosed
WO-2014053661-A1 APPARATUS CONTAINING A DIELECTRIC INSULATION GAS COMPRISING AN ORGANOFLUORINE COMPOUND ABB TECHNOLOGY AG (CH) 2014-04-10 WO disclosed
EP-2652753-A1 DIELECTRIC INSULATION MEDIUM ABB Technology AG (CH) 2013-10-23 EP disclosed
WO-2012080269-A1 DIELECTRIC INSULATION MEDIUM ABB TECHNOLOGY AG (CH) 2012-06-21 WO disclosed
US-20070179263-A1 Functional material comprising fluorine-containing compound DAIKIN INDUSTRIES LTD. (JP) 2007-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070179263-A1 Functional material comprising fluorine-containing compound RER1, AFF1, FRG1 GAA 4694/4885MEN1 174/4885KMT2A 1355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.