Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965022 | 0.86 | MAPT (0.36) | RAB9ANPC1KMT2AALDH1A1GAA | |
| SCHEMBL9964956 | 0.86 | RAB9A (0.36) | RAB9ANPC1KMT2AIDO1TSHR | |
| SCHEMBL9964973 | 0.85 | PIK3CD (0.32) | RAB9ANPC1KMT2ACYP19A1NQO2 | |
| SCHEMBL9964990 | 0.81 | KDM4E (0.36) | RAB9ANPC1KMT2AALDH1A1GAA | |
| SCHEMBL9964978 | 0.79 | CYP19A1 (0.46) | KMT2ACYP19A1NQO2ALDH1A1CYP3A4 | |
| SCHEMBL9964976 | 0.78 | RAB9A (0.34) | RAB9ANPC1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL9964965 | 0.77 | RAB9A (0.33) | RAB9ANPC1KMT2A | |
| SCHEMBL9964961 | 0.73 | MAPT (0.35) | RAB9ANPC1KMT2AALDH1A1GAA | |
| SCHEMBL9964955 | 0.71 | IDO1 (0.33) | IDO1LMNA | |
| SCHEMBL9936519 | 0.71 | ROCK2 (0.33) | KMT2AGAAKDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | claimed |
| US-11013675-B2 | Dye composition comprising a para-phenylenediamine oxidation base and a particular coupler | L'OREAL (FR) | 2021-05-25 | — | — | US | disclosed |
| US-20200108001-A1 | DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A PARTICULAR COUPLER | L'OREAL (FR) | 2020-04-09 | — | — | US | disclosed |
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | disclosed |
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016097022-A1 | DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A PARTICULAR COUPLER | L'OREAL (FR) | 2016-06-23 | — | — | WO | disclosed |
| US-9220671-B2 | Dye composition comprising at least four dye precursors including at least one oxidation base and at least one coupler | L'OREAL (FR) | 2015-12-29 | — | — | US | disclosed |
| US-9220671-B2 | Dye composition comprising at least four dye precursors including at least one oxidation base and at least one coupler | L'OREAL (FR) | 2015-12-29 | — | — | US | disclosed |
| US-9125834-B2 | Dye composition comprising a heterocyclic oxidation base and a 4-aminoindole coupler | L'OREAL (FR) | 2015-09-08 | — | — | US | disclosed |
| US-9125834-B2 | Dye composition comprising a heterocyclic oxidation base and a 4-aminoindole coupler | L'OREAL (FR) | 2015-09-08 | — | — | US | disclosed |
| US-8623100-B2 | 4-aminoindole derivatives and use thereof for the oxidation dyeing of keratin fibres | L'OREAL (FR) | 2014-01-07 | — | — | US | disclosed |
| US-8623100-B2 | 4-aminoindole derivatives and use thereof for the oxidation dyeing of keratin fibres | L'OREAL (FR) | 2014-01-07 | — | — | US | disclosed |
| EP-2651386-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'Oréal (FR) | 2013-10-23 | — | — | EP | disclosed |
| US-20130263390-A1 | 4-AMINOINDOLE DERIVATIVES AND USE THEREOF FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2013-10-10 | — | — | US | disclosed |
| US-20130263390-A1 | 4-AMINOINDOLE DERIVATIVES AND USE THEREOF FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2013-10-10 | — | — | US | disclosed |
| WO-2012080289-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080289-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080321-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080285-A2 | DYE COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080288-A1 | 4-AMINOINDOLE DERIVATIVES AND USE THEREOF FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200108001-A1 | DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A PARTICULAR COUPLER | KRT18, DSG1, PYCR1 | RAB9A 4530/4885NPC1 3996/4885KMT2A 1895/4885 |
| US-11013675-B2 | Dye composition comprising a para-phenylenediamine oxidation base and a particular coupler | KRT18, DSG1, PYCR1 | RAB9A 4530/4885NPC1 3996/4885KMT2A 1895/4885 |
| US-20130263390-A1 | 4-AMINOINDOLE DERIVATIVES AND USE THEREOF FOR THE OXIDATION DYEING OF KERATIN FIBRES | KRT18, AADAT, KMO | RAB9A 3812/4885NPC1 4837/4885KMT2A 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.