SCHEMBL9937352

SCHEMBL9937352

Cc1ccc(C(=O)NCC(NC(=O)O)C(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
NPC1 O15118 3/20 0.48
RAB9A P51151 2/20 0.48
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
ATM Q13315 2/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
MLYCD O95822 1/20 0.44
HPGD P15428 3/20 0.44
MMP13 P45452 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SLC6A9 P48067 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13505507 1.00 LMNA (0.53) LMNAPOLBNPC1RAB9AKMT2A
SCHEMBL30729581 0.84 KMT2A (0.45) LMNAPOLBNPC1RAB9AKMT2A
SCHEMBL13505561 0.84 KMT2A (0.57) LMNAPOLBNPC1RAB9AKMT2A
SCHEMBL21141806 0.84 KMT2A (0.57) LMNAPOLBNPC1RAB9AKMT2A
SCHEMBL14384536 0.83 MAPK14 (0.49) LMNAPOLBNPC1RAB9AKMT2A
SCHEMBL21749693 0.83 LMNA (0.52) LMNAPOLBNPC1RAB9AKMT2A
SCHEMBL20267618 0.81 LMNA (0.53) LMNAPOLBNPC1RAB9AKMT2A
SCHEMBL9937355 0.81 LMNA (0.53) LMNAPOLBNPC1RAB9AKMT2A
SCHEMBL30729578 0.81 CTSK (0.49) LMNAPOLBNPC1RAB9AATM
SCHEMBL21141800 0.80 LMNA (0.51) LMNAPOLBNPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 896 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230413824-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD. (IN) 2023-12-28 US claimed
CN-116801720-A Novel agrochemical compositions comprising 3-substituted benzamidine compounds and uses thereof 皮埃企业有限公司 2023-09-22 CN claimed
US-20230276804-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING PYRAZOLOPYRIDINE ANTHRANILAMIDE COMPOUND, OXIDES OR SALTS THEREOF PI INDUSTRIES LTD. (IN) 2023-09-07 US claimed
US-20230276803-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING THIETANYLOXY COMPOUND, OXIDES OR SALTS THEREOF PI INDUSTRIES LTD. (IN) 2023-09-07 US claimed
CN-116234444-A Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof 皮埃企业有限公司 2023-06-06 CN claimed
EP-4175476-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING THIETANYLOXY COMPOUND, OXIDES OR SALTS THEREOF PI Industries Ltd. (IN) 2023-05-10 EP claimed
EP-4135523-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE Bayer Aktiengesellschaft (DE) 2023-02-22 EP claimed
WO-2022130188-A1 AGROCHEMICAL COMPOSITION COMPRISING PIPERIDINE THIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2022-06-23 WO claimed
WO-2022009058-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING THIETANYLOXY COMPOUND, OXIDES OR SALTS THEREOF PI INDUSTRIES LTD. (IN) 2022-01-13 WO claimed
WO-2021209366-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2021-10-21 WO claimed
US-20150105251-A1 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE SELECTED FROM INHIBITORS OF THE LIPID MEMBRANE SYNTHESIS, THE MELANINE BIOSYNTHESIS, THE NUCLEIC ACID SYNTHESIS OR THE SIGNAL TRANSDUCTION BAYER CROPSCIENCE AG (DE) 2015-04-16 US claimed
US-20140310835-A1 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2014-10-16 US claimed
EP-2699093-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND Bayer Intellectual Property GmbH (DE) 2014-02-26 EP claimed
US-20140038823-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGIDICAL COMPOUND BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-02-06 US claimed
EP-2651209-A2 SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF Syngenta Participations AG (CH) 2013-10-23 EP claimed
EP-2590511-A2 ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES Bayer Intellectual Property GmbH (DE) 2013-05-15 EP claimed
WO-2012143127-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND BAYER CROPSCIENCES AG (DE) 2012-10-26 WO claimed
WO-2012082542-A2 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
WO-2012082548-A2 SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
WO-2012004221-A2 ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES BAYER CROPSCIENCE AG (DE) 2012-01-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230413824-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF CBR3, PFAS, PAH LMNA 4443/4885POLB 3811/4885NPC1 3209/4885
US-20230276804-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING PYRAZOLOPYRIDINE ANTHRANILAMIDE COMPOUND, OXIDES OR SALTS THEREOF ACHE, NOX3, NOX5 LMNA 4233/4885POLB 4001/4885NPC1 4652/4885
US-20230276803-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING THIETANYLOXY COMPOUND, OXIDES OR SALTS THEREOF DDT, ACHE, TH LMNA 4688/4885POLB 4407/4885NPC1 3458/4885
US-20140038823-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGIDICAL COMPOUND AADAC, TUBA3C, NAT1 LMNA 4444/4885POLB 4030/4885NPC1 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.