Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14384536 | 0.85 | MAPK14 (0.49) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30729578 | 0.83 | CTSK (0.49) | LMNAPOLBNPC1RAB9AMAPT | |
| SCHEMBL9937352 | 0.83 | LMNA (0.53) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13505507 | 0.83 | LMNA (0.53) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30729581 | 0.82 | KMT2A (0.45) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13940191 | 0.78 | NPC1 (0.45) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18113985 | 0.77 | MLYCD (0.44) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13940190 | 0.77 | MAPT (0.42) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3810771 | 0.77 | MLYCD (0.44) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29733453 | 0.75 | MLYCD (0.42) | LMNAPOLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11197479-B2 | Use of silthiofam for the treatment of soybean rust | GLOBACHEM NV (BE) | 2021-12-14 | — | — | US | disclosed |
| US-20200060279-A1 | USE OF SILTHIOFAM FOR THE TREATMENT OF SOYBEAN RUST | GLOBACHEM NV (BE) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11197479-B2 | Use of silthiofam for the treatment of soybean rust | TST, LCT, TPST2 | LMNA 2865/4885POLB 4560/4885NPC1 1660/4885 |
| US-20200060279-A1 | USE OF SILTHIOFAM FOR THE TREATMENT OF SOYBEAN RUST | TST, LCT, TPST2 | LMNA 2865/4885POLB 4560/4885NPC1 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.