SCHEMBL9944365

SCHEMBL9944365

Cc1ccc2cccnc2c1C(=O)OC(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.47
ALDH1A1 P00352 6/20 0.47
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 3/20 0.42
MAPT P10636 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HSP90AA1 P07900 2/20 0.42
GMNN O75496 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9945612 0.84 LMNA (0.51) LMNAALDH1A1CCR1CCR5CCR8
SCHEMBL11430231 0.79 LMNA (0.56) LMNAALDH1A1CCR1CCR5CCR8
SCHEMBL28189404 0.78 LMNA (0.51) LMNAALDH1A1CCR1CCR5CCR8
SCHEMBL9944361 0.78 ALDH1A1 (0.60) LMNAALDH1A1CA12CA1CA2
SCHEMBL9944372 0.74 KDM4E (0.52) LMNAALDH1A1CA12CA1CA2
SCHEMBL9944366 0.73 ALDH1A1 (0.43) LMNAALDH1A1L3MBTL1KDM4EMAPT
SCHEMBL6067981 0.72 CA12 (0.68) LMNAALDH1A1CA12CA1CA2
SCHEMBL9944385 0.72 ELANE (0.46) LMNAALDH1A1CA12CA1CA2
SCHEMBL14649881 0.72 CA12 (0.49) LMNAALDH1A1CA12CA1CA2
SCHEMBL2222695 0.70 CA12 (0.46) LMNAALDH1A1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846291-B2 Resist composition, method of forming resist pattern, and new compound TOKYO OHKA KOGYO CO. LTD. (JP) 2014-09-30 US disclosed
US-20120148955-A1 RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, AND NEW COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120148955-A1 RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, AND NEW COMPOUND C1R, SLC11A2, RER1 LMNA 1036/4885ALDH1A1 2007/4885CA12 1296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.