Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.58 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | INMT | O95050 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12020265 | 0.97 | APOBEC3A (0.61) | APOBEC3AAPOBEC3GALDH1A1TDP1KDM4E | |
| SCHEMBL1684199 | 0.97 | APOBEC3A (0.61) | APOBEC3AAPOBEC3GALDH1A1TDP1KDM4E | |
| SCHEMBL7546309 | 0.93 | APOBEC3A (0.58) | APOBEC3AAPOBEC3GALDH1A1TDP1KDM4E | |
| SCHEMBL7546306 | 0.93 | APOBEC3A (0.58) | APOBEC3AAPOBEC3GALDH1A1TDP1KDM4E | |
| Iodide SCHEMBL5085390 | 0.93 | APOBEC3A (0.67) | APOBEC3AAPOBEC3GALDH1A1TDP1KDM4E | |
| Bromide SCHEMBL5092593 | 0.93 | APOBEC3A (0.58) | APOBEC3AAPOBEC3GALDH1A1TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL2320632 | 0.93 | APOBEC3A (0.58) | APOBEC3AAPOBEC3GALDH1A1TDP1KDM4E | |
| Boric Acid SCHEMBL11811405 | 0.85 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GALDH1A1TDP1KDM4E | |
| SCHEMBL7637767 | 0.85 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GALDH1A1TDP1KDM4E | |
| SCHEMBL2318951 | 0.83 | ALDH1A1 (0.52) | APOBEC3AAPOBEC3GALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12173150-B2 | Polyester carbonates from cycloaliphatic diacids and aliphatic diols, and process for preparing same | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2024-12-24 | — | — | US | claimed |
| US-20220073737-A1 | POLYESTER CARBONATES FROM CYCLOALIPHATIC DIACIDS AND ALIPHATIC DIOLS, AND PROCESS FOR PREPARING SAME | COVESTRO DEUTSCHLAND AG (DE) | 2022-03-10 | — | — | US | claimed |
| EP-3898764-A1 | POLYESTER CARBONATES FROM CYCLOALIPHATIC DIACIDS AND ALIPHATIC DIOLS, AND PROCESS FOR PREPARING SAME | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-10-27 | — | — | EP | claimed |
| CN-113166384-A | Polyester carbonates made from cycloaliphatic diacids and aliphatic diols and methods for making the same | 科思创知识产权两合公司 | 2021-07-23 | — | — | CN | claimed |
| WO-2020126806-A1 | POLYESTER CARBONATES FROM CYCLOALIPHATIC DIACIDS AND ALIPHATIC DIOLS, AND PROCESS FOR PREPARING SAME | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2020-06-25 | — | — | WO | claimed |
| EP-4526369-B1 | POLYSILOXANE POLYCARBONATE BLOCK COPOLYMERS FROM SPECIALLY TERMINATED SILOXANE BLOCKS | COVESTRO DEUTSCHLAND AG (DE) | 2026-03-04 | — | — | EP | disclosed |
| EP-4514878-B1 | AMORPHOUS COPOLYCARBONATE WITH PHENOLIC BUILDING BLOCKS | COVESTRO DEUTSCHLAND AG (DE) | 2026-03-04 | — | — | EP | disclosed |
| EP-3055342-B1 | PROCESS FOR PREPARING POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES USING A SALT OF A WEAK ACID | COVESTRO DEUTSCHLAND AG (DE) | 2026-03-04 | — | — | EP | disclosed |
| EP-4514877-B1 | POLYCARBONATE COCONDENSATE WITH PHENOLIC BUILDING BLOCKS | COVESTRO DEUTSCHLAND AG (DE) | 2026-03-04 | — | — | EP | disclosed |
| US-12534568-B2 | Polyester carbonates consisting of different diols in a defined ratio | COVESTRO DEUTSCHLAND AG (DE) | 2026-01-27 | — | — | US | disclosed |
| US-12516152-B2 | Polyester carbonates having a defined proportion of ester groups | COVESTRO DEUTSCHLAND AG (DE) | 2026-01-06 | — | — | US | disclosed |
| US-20250326896-A1 | Polysiloxane-Polycarbonate Block Co-Condensates Composed of Specially Terminated Siloxane Blocks | COVESTRO DEUTSCHLAND AG (DE) | 2025-10-23 | — | — | US | disclosed |
| US-4320029-A | Catalytic composite, method of manufacture, and process for use | UOP INC. (US) | 1982-03-16 | — | — | US | disclosed |
| US-4308169-A | TREATMENT WITH AQUEOUS SOLUTION OF QUATERNARY AMMONIUM COMPOUND AND LINEAR IONIC COMPOUND | UOP INC. (US) | 1981-12-29 | — | — | US | disclosed |
| US-4299729-A | TREATING WITH AN AMMONIACAL SOLUTION OF A METAL CHELATE AND AN AQUEOUS SOLUTION OF A QUATERNARY AMMONIUM COMPOUND | UOP INC. (US) | 1981-11-10 | — | — | US | disclosed |
| US-4298463-A | Method of treating a sour petroleum distillate | UOP INC. (US) | 1981-11-03 | — | — | US | disclosed |
| US-4213877-A | Method of reactivating a catalytic composite of an adsorptive carrier material and a mercaptan oxidation catalyst | UOP INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4203827-A | Process for treating sour petroleum distillates | UOP INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-3977996-A | CHROMIUM (III) CARBOXYLATE, COCATALYST | AEROJET-GENERAL CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
| US-3978026-A | SYNERGISTIC, CHROMIUMIII TRICARBOXYLATE, COCATALYST | AEROJET-GENERAL CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534568-B2 | Polyester carbonates consisting of different diols in a defined ratio | HSD11B2, HSD11B1, HSD3B1 | APOBEC3A 4431/4885APOBEC3G 4330/4885ALDH1A1 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.