Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944832 | 0.84 | HCAR3 (0.40) | KDM1AALDH1A1L3MBTL1HCAR3HTT | |
| SCHEMBL9944736 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HCAR3CDC25BHPGD | |
| SCHEMBL1727200 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HCAR3CDC25BPTGESHPGD | |
| SCHEMBL1727199 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HCAR3CDC25BPTGESHPGD | |
| SCHEMBL9944828 | 0.80 | MAPT (0.43) | ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL9944735 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HCAR3CDC25BPTGESTYK2 | |
| SCHEMBL9899508 | 0.78 | PTGES (0.44) | ALDH1A1L3MBTL1HCAR3CDC25BPTGES | |
| SCHEMBL9899506 | 0.78 | PTGES (0.44) | ALDH1A1L3MBTL1HCAR3CDC25BPTGES | |
| SCHEMBL9944988 | 0.76 | NPC1 (0.44) | ALDH1A1L3MBTL1HCAR3HTTCDC25B | |
| SCHEMBL11951407 | 0.76 | HTT (0.49) | ALDH1A1L3MBTL1HCAR3HTTCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | KDM1A 1720/4885ALDH1A1 126/4885L3MBTL1 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.