Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899508 | 0.89 | PTGES (0.44) | ALDH1A1HCAR3PKMPTGESTYK2 | |
| SCHEMBL9899506 | 0.89 | PTGES (0.44) | ALDH1A1HCAR3PKMPTGESTYK2 | |
| SCHEMBL9944733 | 0.84 | RAB9A (0.42) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9944736 | 0.82 | ALDH1A1 (0.47) | ALDH1A1RAB9AHCAR3NPC1TAS1R3 | |
| SCHEMBL9944819 | 0.81 | ALDH1A1 (0.41) | ALDH1A1RAB9ANPC1TAS1R3TAS1R1 | |
| SCHEMBL9944832 | 0.81 | HCAR3 (0.40) | ALDH1A1HCAR3CDC25BMAPT | |
| SCHEMBL9944828 | 0.80 | MAPT (0.43) | ALDH1A1POLBGAAMAPT | |
| SCHEMBL9944747 | 0.80 | ALDH1A1 (0.53) | ALDH1A1RAB9AHCAR3NPC1TAS1R3 | |
| SCHEMBL9945003 | 0.80 | ALDH1A1 (0.53) | ALDH1A1RAB9AHCAR3NPC1TAS1R3 | |
| SCHEMBL9944827 | 0.80 | KDM1A (0.40) | ALDH1A1HCAR3PKMPTGESTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | ALDH1A1 126/4885RAB9A 1033/4885HCAR3 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.