Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944827 | 0.84 | KDM1A (0.40) | HCAR3ALDH1A1MAPTL3MBTL1HTT | |
| SCHEMBL9944833 | 0.82 | KDM1A (0.36) | ALDH1A1MAPTHTTKDM1A | |
| SCHEMBL9944735 | 0.81 | ALDH1A1 (0.42) | HCAR3ALDH1A1MAPTCDC25B | |
| SCHEMBL9899508 | 0.78 | PTGES (0.44) | HCAR3ALDH1A1MAPTL3MBTL1CDC25B | |
| SCHEMBL9899506 | 0.78 | PTGES (0.44) | HCAR3ALDH1A1MAPTL3MBTL1CDC25B | |
| SCHEMBL9944828 | 0.77 | MAPT (0.43) | ALDH1A1MAPTHTTLMNA | |
| SCHEMBL9944895 | 0.73 | ALDH1A1 (0.42) | HCAR3ALDH1A1MAPTLMNA | |
| SCHEMBL9947086 | 0.73 | ALDH1A1 (0.46) | HCAR3ALDH1A1L3MBTL1HTTCDC25B | |
| SCHEMBL12494815 | 0.72 | ALDH1A1 (0.54) | HCAR3ALDH1A1MAPTL3MBTL1HTT | |
| SCHEMBL12495181 | 0.72 | ALDH1A1 (0.48) | HCAR3ALDH1A1MAPTL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | HCAR3 228/4885ALDH1A1 126/4885MAPT 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.