SCHEMBL9949895

SCHEMBL9949895

NC(=O)OC(=O)c1ccc(N)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.51
CHRM3 P20309 1/20 0.51
MAOA P21397 1/20 0.51
HTR2C P28335 1/20 0.51
CHRNA4 P43681 1/20 0.51
HTR3A P46098 1/20 0.51
KCNH2 Q12809 1/20 0.51
HRH3 Q9Y5N1 1/20 0.51
NR1H4 Q96RI1 1/20 0.48
JAK2 O60674 1/20 0.45
TYK2 P29597 1/20 0.45
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
GAA P10253 2/20 0.42
NPC1 O15118 6/20 0.42
RAB9A P51151 6/20 0.42
HPGD P15428 5/20 0.42
CYP3A4 P08684 5/20 0.42
TSHR P16473 2/20 0.42
CASP3 P42574 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27447975 0.81 MAPT (0.44) CHRM2CHRM3MAOAHTR2CCHRNA4
SCHEMBL9949356 0.80 GAA (0.66) CA1CA2GAAHPGDCYP3A4
SCHEMBL145288 0.80 GAA (0.66) CHRM2CHRM3MAOAHTR2CCHRNA4
SCHEMBL2335079 0.79 KMT2A (0.55) CHRM2CHRM3MAOAHTR2CCHRNA4
SCHEMBL9949367 0.79 GAA (0.42) CHRM2CHRM3MAOAHTR2CCHRNA4
SCHEMBL9949713 0.79 ADRB2 (0.47) MAOAGAANPC1RAB9AHPGD
Hydrochloric Acid SCHEMBL3865922 0.79 GAA (0.64) CHRM2CHRM3MAOAHTR2CCHRNA4
SCHEMBL7090488 0.77 JAK2 (0.53) CHRM2CHRM3MAOAHTR2CCHRNA4
SCHEMBL753194 0.76 MAOA (0.68) CHRM2CHRM3MAOAHTR2CCHRNA4
SCHEMBL355647 0.76 NR1H4 (0.56) CHRM2CHRM3MAOAHTR2CCHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120165315-A1 MEPTAZINOL CARBAMATE PRODRUG SALTS JOSTENS, INC. 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165315-A1 MEPTAZINOL CARBAMATE PRODRUG SALTS MEP1A, MEP1B, CTSZ CHRM2 106/4885CHRM3 77/4885MAOA 551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.