Ethylene

Ethylene

SCHEMBL9949458

C=C.CCC(c1ccc(C=O)cc1)C1CCCCC1.CCOC(C)OCC

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MITF O75030 1/20 0.37
TYR P14679 1/20 0.36
ALDH1A3 P47895 1/20 0.34
BCHE P06276 5/20 0.34
ACHE P22303 5/20 0.34
PTGS2 P35354 5/20 0.34
PKM P14618 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
ALDH1A1 P00352 2/20 0.33
FFAR1 O14842 1/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A3 Q01959 2/20 0.32
SLC6A4 P31645 1/20 0.32
LMNA P02545 3/20 0.32
HTT P42858 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL9950475 0.88 TYR (0.38) MEN1KMT2AMITFTYRALDH1A3
SCHEMBL9949983 0.87 TYR (0.43) MEN1KMT2AMITFTYRALDH1A3
Cyclopropane SCHEMBL6228970 0.80 LMNA (0.46) TYRALDH1A3BCHEACHEPTGS2
Ethylene SCHEMBL9950993 0.79 TYR (0.35) TYRALDH1A3BCHEACHEPTGS2
Ethylene SCHEMBL6226363 0.78 LMNA (0.48) TYRALDH1A3BCHEACHEPTGS2
Ethylene SCHEMBL9949858 0.78 ACHE (0.34) TYRALDH1A3BCHEACHEPTGS2
Ethylene SCHEMBL9950782 0.78 LTA4H (0.35) ALDH1A3PTGS2ALDH1A1FFAR1LMNA
Ethylene SCHEMBL9950177 0.77 TYR (0.36) TYRALDH1A3BCHEACHEPTGS2
Ethylene SCHEMBL9951283 0.77 TYR (0.37) TYRALDH1A3BCHEACHEPTGS2
Ethylene SCHEMBL9949580 0.76 TYR (0.35) TYRALDH1A3BCHEACHEPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2476662-B1 CYCLIC COMPOUND, PROCESS FOR PREPARATION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND METHOD FOR FORMATION OF RESIST PATTERN MITSUBISHI GAS CHEMICAL CO (JP) 2018-05-30 EP claimed
EP-2476662-B1 CYCLIC COMPOUND, PROCESS FOR PREPARATION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND METHOD FOR FORMATION OF RESIST PATTERN MITSUBISHI GAS CHEMICAL CO (JP) 2018-05-30 EP disclosed
US-8748078-B2 Cyclic compound, process for preparation thereof, radiation-sensitive composition, and method for formation of resist pattern MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-06-10 US disclosed
EP-2476662-A1 CYCLIC COMPOUND, PROCESS FOR PREPARATION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND METHOD FOR FORMATION OF RESIST PATTERN Mitsubishi Gas Chemical Company, Inc. (JP) 2012-07-18 EP disclosed
US-20120164576-A1 CYCLIC COMPOUND, PROCESS FOR PREPARATION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND METHOD FOR FORMATION OF RESIST PATTERN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120164576-A1 CYCLIC COMPOUND, PROCESS FOR PREPARATION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND METHOD FOR FORMATION OF RESIST PATTERN RAD1, RER1, REV1 MEN1 187/4885KMT2A 3487/4885MITF 4276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.