Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109078 | 0.93 | PAOX (0.61) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL110911 | 0.91 | PAOX (0.64) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Hydrochloric Acid SCHEMBL21772194 | 0.91 | PAOX (0.59) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL3508069 | 0.91 | PAOX (0.64) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Hydrochloric Acid SCHEMBL29050250 | 0.89 | PAOX (0.62) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Hydrochloric Acid SCHEMBL21772210 | 0.89 | PAOX (0.62) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Phosphoric Acid SCHEMBL9950456 | 0.87 | PAOX (0.35) | PAOXCA12CA1CA2CA9 | |
| SCHEMBL28954974 | 0.87 | PAOX (0.52) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Phosphoric Acid SCHEMBL3769852 | 0.87 | CA12 (0.41) | PAOXCA12CA1CA2CA9 | |
| SCHEMBL49567 | 0.87 | PAOX (0.52) | PAOXGNAI3GNAO1GNAI1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102531943-B | Novel compound and method for preparing the same | FUJIFILM CORP | 2015-05-27 | — | — | CN | disclosed |
| US-8722931-B2 | Compound and method for preparing the same | FUJIFILM CORPORATION (JP) | 2014-05-13 | — | — | US | disclosed |
| EP-2468715-B1 | Novel compound and method for preparing the same | FUJIFILM CORP (JP) | 2013-04-17 | — | — | EP | disclosed |
| US-20120165572-A1 | NOVEL COMPOUND AND METHOD FOR PREPARING THE SAME | FUJIFILM CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
| EP-2468715-A1 | Novel compound and method for preparing the same | Fujifilm Corporation (JP) | 2012-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165572-A1 | NOVEL COMPOUND AND METHOD FOR PREPARING THE SAME | ADCY1, ADCY2, ADCY5 | PAOX 2295/4885GNAI3 548/4885GNAO1 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.