Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.38 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.38 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.59 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29050250 | 0.98 | PAOX (0.62) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Hydrochloric Acid SCHEMBL21772210 | 0.98 | PAOX (0.62) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL109078 | 0.98 | PAOX (0.61) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL3508069 | 0.96 | PAOX (0.64) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL110911 | 0.96 | PAOX (0.64) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Hydrochloric Acid SCHEMBL28412040 | 0.94 | PAOX (0.50) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Hydrochloric Acid SCHEMBL82715 | 0.94 | PAOX (0.50) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL28954974 | 0.92 | PAOX (0.52) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL49567 | 0.92 | PAOX (0.52) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL15271425 | 0.91 | PAOX (0.53) | PAOXGNAI3GNAO1GNAI1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024245021-A1 | AMINO-CONTAINING POLYMER, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海微密医疗科技有限公司 | 2024-12-05 | — | — | WO | claimed |
| CN-116333217-B | Preparation method of amino-containing polymer, polymer product and application | 上海微密医疗科技有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-116333217-A | Preparation method of amino-containing polymer, polymer product and application | 上海微密医疗科技有限公司 | 2023-06-27 | — | — | CN | claimed |
| US-10703835-B2 | Hyperbranched cationic mussel-imitated polymer and method of preparing the same | Sichuan Huili Industry Co., Ltd. (CN) | 2020-07-07 | — | — | US | claimed |
| US-20200071433-A1 | HYPERBRANCHED CATIONIC MUSSEL-IMITATED POLYMER AND METHOD OF PREPARING THE SAME | Sichuan Huili Industry Co., Ltd. (CN) | 2020-03-05 | — | — | US | claimed |
| CN-109096450-A | Imitative mussel polymer of the hyperbranched cation of one kind and preparation method thereof | 四川汇利实业有限公司 | 2018-12-28 | — | — | CN | claimed |
| WO-2024245021-A1 | AMINO-CONTAINING POLYMER, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海微密医疗科技有限公司 | 2024-12-05 | — | — | WO | disclosed |
| CN-116333217-B | Preparation method of amino-containing polymer, polymer product and application | 上海微密医疗科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116333217-A | Preparation method of amino-containing polymer, polymer product and application | 上海微密医疗科技有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-11318724-B2 | Film for medicine packaging and method of preparing the same | Sichuan Huili Industry Co., Ltd. (CN) | 2022-05-03 | — | — | US | disclosed |
| US-20200282714-A1 | FILM FOR MEDICINE PACKAGING AND METHOD OF PREPARING THE SAME | SICHUAN HUILI IND CO LTD (CN) | 2020-09-10 | — | — | US | disclosed |
| US-10703835-B2 | Hyperbranched cationic mussel-imitated polymer and method of preparing the same | Sichuan Huili Industry Co., Ltd. (CN) | 2020-07-07 | — | — | US | disclosed |
| US-10703080-B2 | Film for medicine packaging and method of preparing the same | Sichuan Huili Industry Co., Ltd. (CN) | 2020-07-07 | — | — | US | disclosed |
| US-20200071433-A1 | HYPERBRANCHED CATIONIC MUSSEL-IMITATED POLYMER AND METHOD OF PREPARING THE SAME | Sichuan Huili Industry Co., Ltd. (CN) | 2020-03-05 | — | — | US | disclosed |
| US-20200070485-A1 | FILM FOR MEDICINE PACKAGING AND METHOD OF PREPARING THE SAME | Sichuan Huili Industry Co., Ltd. (CN) | 2020-03-05 | — | — | US | disclosed |