SCHEMBL9950188

SCHEMBL9950188

COS(=O)(=O)c1cc(Cl)cc(S(=O)(=O)OC)c1-c1c(S(=O)(=O)OC)cc(Cl)cc1S(=O)(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.38
F2 P00734 2/20 0.38
PRSS1 P07477 2/20 0.38
PRSS2 P07478 2/20 0.38
PRSS3 P35030 2/20 0.38
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
CA9 Q16790 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TSHR P16473 2/20 0.33
TP53 P04637 1/20 0.33
NPC1 O15118 1/20 0.33
ACLY P53396 2/20 0.33
ALPL P05186 1/20 0.33
WDR5 P61964 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9950008 0.88 CASR (0.36) TRPV4F2PRSS1PRSS2PRSS3
SCHEMBL9950001 0.88 F2 (0.36) TRPV4F2PRSS1PRSS2PRSS3
SCHEMBL5318058 0.79 ALDH1A1 (0.49) TRPV4ALDH1A1KDM4EPOLBHPGD
SCHEMBL811473 0.79 TRPV4 (0.46) TRPV4ALDH1A1KDM4EPOLBHPGD
SCHEMBL15352925 0.79 TRPV4 (0.46) TRPV4ALDH1A1KDM4EPOLBHPGD
SCHEMBL6189340 0.77 ERN1 (0.44) TRPV4F2PRSS1PRSS2PRSS3
SCHEMBL13290848 0.76 TSHR (0.38) TRPV4CA1CA2ALDH1A1CA9
SCHEMBL9952113 0.76 TSHR (0.36) TRPV4F2PRSS1PRSS2PRSS3
SCHEMBL15352671 0.76 TUBB4A (0.40) F2PRSS1PRSS2PRSS3CA1
SCHEMBL13290781 0.76 ALDH1A1 (0.58) TRPV4ALDH1A1KDM4EPOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120164558-A1 BIPHENYLTETRASULFONIC ACID COMPOUND, METHOD FOR PRODUCING SAME, POLYMER AND POLYMER ELECTROLYTE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120164558-A1 BIPHENYLTETRASULFONIC ACID COMPOUND, METHOD FOR PRODUCING SAME, POLYMER AND POLYMER ELECTROLYTE ARSA, PDXK, AIPL1 TRPV4 3456/4885F2 592/4885PRSS1 1819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.