Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9951090 | 0.76 | HCRTR2 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL10189151 | 0.74 | HCRTR2 (0.58) | HCRTR1HCRTR2MEN1KMT2ANPSR1 | |
| SCHEMBL11024703 | 0.60 | ALDH1A1 (0.69) | RAB9ALMNATSHRL3MBTL1HTT | |
| SCHEMBL9951443 | 0.59 | HSD11B1 (0.38) | HCRTR1HCRTR2RAB9AMEN1KMT2A | |
| SCHEMBL4124368 | 0.57 | L3MBTL1 (0.75) | RAB9ALMNATSHRL3MBTL1MEN1 | |
| SCHEMBL11034892 | 0.56 | TDP1 (0.69) | RAB9ALMNATSHRL3MBTL1KMT2A | |
| Trifluoroacetic Acid SCHEMBL28688522 | 0.55 | L3MBTL1 (0.55) | RAB9ALMNATSHRL3MBTL1KMT2A | |
| Trifluoroacetic Acid SCHEMBL29557332 | 0.55 | L3MBTL1 (0.55) | RAB9ALMNATSHRL3MBTL1MEN1 | |
| Trifluoroacetic Acid SCHEMBL28707111 | 0.55 | L3MBTL1 (0.55) | RAB9ALMNATSHRL3MBTL1MEN1 | |
| SCHEMBL7069217 | 0.55 | KMT2A (0.79) | RAB9ATSHRL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165339-A1 | CYCLOPROPANE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165339-A1 | CYCLOPROPANE DERIVATIVES | HCRTR2, HCRTR1, CNR1 | HCRTR1 2/4885HCRTR2 1/4885RAB9A 1468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.