SCHEMBL9952055

SCHEMBL9952055

CCSc1cccc(C(F)(F)F)c1-c1nccn1COC

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.34
TP53 P04637 1/20 0.34
AR P10275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9952851 0.90 TP53 (0.33) P2RX7TP53AR
SCHEMBL9952650 0.89 P2RX7 (0.36) P2RX7TP53AR
SCHEMBL9953091 0.79 NFE2L2 (0.36) P2RX7
SCHEMBL9952936 0.73 NPC1 (0.35) TP53AR
SCHEMBL9952318 0.71 ALDH1A1 (0.35) TP53
SCHEMBL9952746 0.69 GABRG2 (0.44) P2RX7AR
SCHEMBL9954038 0.69 GABRA1 (0.43) P2RX7AR
SCHEMBL9953333 0.68 HTR2C (0.33)
SCHEMBL9953787 0.68 PTPN1 (0.40) P2RX7
SCHEMBL9952807 0.68 HTR2C (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655337-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF Sumitomo Chemical Company Limited (JP) 2013-10-30 EP disclosed
WO-2012086848-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-06-28 WO disclosed