Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.40 |
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
| ▸ | CCND1 | P24385 | 4/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289133 | 0.82 | CACNA2D1 (0.39) | KMT2AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL9953326 | 0.80 | PI4KA (0.45) | KMT2AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL9952794 | 0.80 | HCAR1 (0.41) | KMT2AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL9953300 | 0.68 | PDE5A (0.46) | KMT2AALDH1A1PDE4BPDE4DMEN1 | |
| SCHEMBL31241110 | 0.68 | PDE5A (0.46) | KMT2AALDH1A1PDE4BPDE4DMEN1 | |
| SCHEMBL17583061 | 0.68 | HCAR1 (0.45) | KMT2AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL14247637 | 0.68 | HCAR1 (0.48) | KMT2AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL10289136 | 0.67 | CACNA2D1 (0.51) | KMT2AMAPTOPRM1MEN1ATM | |
| SCHEMBL9953980 | 0.67 | ATM (0.51) | KMT2AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL21090745 | 0.66 | CTSD (0.50) | LMNAKMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |