Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952794 | 0.85 | HCAR1 (0.41) | ATMKMT2AMEN1HCAR1CTSD | |
| SCHEMBL14247586 | 0.82 | CCNC (0.43) | PIK3CAATMMTORATRHCAR1 | |
| SCHEMBL9953287 | 0.80 | LMNA (0.40) | PI4KAPIK3CGPIK3CAATMKMT2A | |
| SCHEMBL10289133 | 0.80 | CACNA2D1 (0.39) | ATMMTORKMT2AMEN1CTSD | |
| SCHEMBL16204803 | 0.74 | HCAR1 (0.52) | ATMKMT2AMEN1HCAR1MAPT | |
| SCHEMBL9953779 | 0.73 | ALOX15 (0.55) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL10289137 | 0.73 | PI4KA (0.62) | PI4KAPIK3CGPIK3CAATMMTOR | |
| SCHEMBL9953300 | 0.72 | PDE5A (0.46) | ATMKMT2AMEN1CTSDALDH1A1 | |
| SCHEMBL31241110 | 0.72 | PDE5A (0.46) | ATMKMT2AMEN1CTSDALDH1A1 | |
| SCHEMBL9960599 | 0.71 | MAPK1 (0.49) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |