Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954119 | 0.85 | HCAR1 (0.52) | TDO2IDO2HCAR1 | |
| SCHEMBL9955332 | 0.84 | HCAR1 (0.51) | TDO2IDO2HCAR1 | |
| SCHEMBL9954105 | 0.81 | HCAR1 (0.53) | TDO2IDO2HCAR1 | |
| SCHEMBL9952976 | 0.81 | LMNA (0.45) | TDO2IDO2HCAR1 | |
| SCHEMBL9953657 | 0.81 | HCAR1 (0.56) | PDE4DTDO2IDO2HCAR1 | |
| SCHEMBL9954457 | 0.79 | HCAR1 (0.50) | HCAR1CA12CA1CA2CA9 | |
| SCHEMBL9954370 | 0.79 | L3MBTL1 (0.51) | — | |
| SCHEMBL9954540 | 0.78 | HCAR1 (0.58) | TDO2IDO2HCAR1 | |
| SCHEMBL9955025 | 0.78 | ESR2 (0.41) | CA12CA1CA2CA9 | |
| SCHEMBL9953534 | 0.78 | HCAR1 (0.43) | PDE4DTDO2IDO2HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |