Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954119 | 0.84 | HCAR1 (0.52) | HCAR1TDO2IDO2LMNAL3MBTL1 | |
| SCHEMBL9954005 | 0.84 | HCAR1 (0.40) | HCAR1PDE4DALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9952718 | 0.82 | TDO2 (0.48) | TDO2IDO2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL9954224 | 0.81 | CDK9 (0.38) | HCAR1PDE4DTDO2IDO2ALDH1A1 | |
| SCHEMBL9952976 | 0.81 | LMNA (0.45) | HCAR1TDO2IDO2ALDH1A1LMNA | |
| SCHEMBL9955332 | 0.80 | HCAR1 (0.51) | HCAR1TDO2IDO2ALDH1A1LMNA | |
| SCHEMBL9953501 | 0.80 | HPD (0.47) | HCAR1TDO2IDO2ALDH1A1L3MBTL1 | |
| SCHEMBL9954657 | 0.80 | HPD (0.44) | HCAR1TDO2IDO2POLB | |
| SCHEMBL9954234 | 0.80 | ALDH1A1 (0.53) | HCAR1TDO2IDO2ALDH1A1TP53 | |
| SCHEMBL9954749 | 0.79 | PDE7A (0.45) | HCAR1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |