Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPD | P32754 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954119 | 0.88 | HCAR1 (0.52) | HCAR1LMNAHPDTDO2IDO2 | |
| SCHEMBL9954747 | 0.87 | HCAR1 (0.53) | HCAR1LMNATP53ALDH1A1POLB | |
| SCHEMBL9954105 | 0.87 | HCAR1 (0.53) | HCAR1TP53HPDTDO2IDO2 | |
| SCHEMBL9952976 | 0.87 | LMNA (0.45) | HCAR1LMNATP53ALDH1A1IDO1 | |
| SCHEMBL9954457 | 0.85 | HCAR1 (0.50) | HCAR1SMN1; SMN2 | |
| SCHEMBL6214003 | 0.84 | TDO2 (0.57) | TDO2IDO2 | |
| SCHEMBL9954370 | 0.84 | L3MBTL1 (0.51) | LMNATP53ALDH1A1HPD | |
| SCHEMBL9953657 | 0.84 | HCAR1 (0.56) | HCAR1LMNAALDH1A1POLBTDO2 | |
| SCHEMBL9953531 | 0.84 | PDE4D (0.42) | HCAR1TDO2IDO2 | |
| SCHEMBL9954540 | 0.81 | HCAR1 (0.58) | HCAR1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |