Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | HPD | P32754 | 2/20 | 0.44 |
| ▸ | PI4KA | P42356 | 9/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954423 | 0.88 | POLB (0.41) | TGM2PI4KAPIK3CGPIK3CD | |
| SCHEMBL9953324 | 0.87 | HCAR1 (0.50) | PI4KAPIK3CG | |
| SCHEMBL9954651 | 0.86 | POLB (0.53) | HPDPI4KAPIK3CG | |
| SCHEMBL9954657 | 0.85 | HPD (0.44) | TGM2HPD | |
| SCHEMBL9955586 | 0.85 | HPD (0.44) | HPDPI4KAPIK3CG | |
| SCHEMBL9955061 | 0.84 | PIK3CG (0.48) | PI4KAPIK3CGPIK3CD | |
| SCHEMBL9953795 | 0.83 | SMN1; SMN2 (0.55) | HPDPI4KAPIK3CG | |
| SCHEMBL9954505 | 0.82 | PDE7A (0.45) | PI4KA | |
| SCHEMBL9954546 | 0.82 | PI4KA (0.44) | PI4KAPIK3CG | |
| SCHEMBL9952904 | 0.80 | GLA (0.51) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |