Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.40 |
| ▸ | PI4KA | P42356 | 5/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954651 | 0.89 | POLB (0.53) | POLBPI4KATDO2IDO2IDO1 | |
| SCHEMBL9953665 | 0.88 | TGM2 (0.45) | PIK3CDPI4KAPIK3CGTGM2 | |
| SCHEMBL9953324 | 0.85 | HCAR1 (0.50) | PI4KACA12CA1CA2CA9 | |
| SCHEMBL9953129 | 0.84 | POLB (0.41) | POLBPIK3CDPIK3R1TDO2IDO2 | |
| SCHEMBL9953800 | 0.84 | POLB (0.41) | POLBPI4KACA12CA1CA2 | |
| SCHEMBL9954094 | 0.81 | HCAR1 (0.51) | POLBPI4KACA12CA1CA2 | |
| SCHEMBL9953556 | 0.81 | CA12 (0.42) | POLBCA12CA1CA2CA9 | |
| SCHEMBL9952904 | 0.81 | GLA (0.51) | POLBPI4KATDO2IDO2IDO1 | |
| SCHEMBL9954066 | 0.81 | PI4KA (0.46) | POLBPI4KACA12CA1CA2 | |
| SCHEMBL9954505 | 0.80 | PDE7A (0.45) | PI4KATDO2IDO2TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |