Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPD | P32754 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953670 | 0.85 | ALDH1A1 (0.44) | ATMMAPTLMNAMEN1KMT2A | |
| SCHEMBL10289023 | 0.79 | SMN1; SMN2 (0.49) | POLBMAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL10288659 | 0.78 | POLB (0.53) | POLBATMMAPTPDE7ALMNA | |
| SCHEMBL9954482 | 0.76 | CCKBR (0.40) | ATMMAPTPDE7ALMNASMN1; SMN2 | |
| SCHEMBL9952861 | 0.76 | TDO2 (0.46) | ATMMAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL31241102 | 0.73 | CACNA2D1 (0.42) | ATMMAPTHPGDMEN1KMT2A | |
| SCHEMBL9953155 | 0.73 | ATM (0.48) | ATMMAPTPDE7AMEN1KMT2A | |
| SCHEMBL9954454 | 0.70 | MEN1 (0.41) | POLBATMMAPTLMNAHPGD | |
| SCHEMBL9954225 | 0.68 | ALDH1A1 (0.52) | ATMMAPTLMNAHPGDMEN1 | |
| SCHEMBL9952928 | 0.68 | KMT2A (0.53) | POLBMAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |