Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 2/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289023 | 0.82 | SMN1; SMN2 (0.49) | CCKBRMAPTALDH1A1HPDSMN1; SMN2 | |
| SCHEMBL9955086 | 0.82 | CCKBR (0.43) | CCKBRIDO1TDO2IDO2MAPT | |
| SCHEMBL9952861 | 0.77 | TDO2 (0.46) | TDO2IDO2MAPTATMALDH1A1 | |
| SCHEMBL9954435 | 0.76 | POLB (0.47) | IDO1TDO2IDO2MAPTATM | |
| SCHEMBL9953670 | 0.76 | ALDH1A1 (0.44) | MAPTATMALDH1A1HPDLMNA | |
| SCHEMBL9953155 | 0.71 | ATM (0.48) | CCKBRIDO1TDO2IDO2MAPT | |
| SCHEMBL31241102 | 0.71 | CACNA2D1 (0.42) | MAPTATMALDH1A1 | |
| SCHEMBL9955108 | 0.71 | MEN1 (0.40) | ATMALDH1A1SMN1; SMN2 | |
| SCHEMBL24090098 | 0.70 | TDO2 (0.49) | IDO1TDO2IDO2ALDH1A1 | |
| SCHEMBL24090011 | 0.70 | ACP1 (0.50) | CCKBRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |