Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 2/20 | 0.39 |
| ▸ | PI4KA | P42356 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954482 | 0.82 | CCKBR (0.40) | CCKBRIDO1TDO2IDO2ATM | |
| SCHEMBL9953980 | 0.81 | ATM (0.51) | IDO1TDO2IDO2ATMMAPT | |
| SCHEMBL10289024 | 0.80 | SMN1; SMN2 (0.55) | CCKBRMAPTALDH1A1HPDPI4KA | |
| SCHEMBL9955586 | 0.75 | HPD (0.44) | HPDPI4KAPIK3CGSMN1; SMN2MEN1 | |
| SCHEMBL9954589 | 0.75 | ALOX12 (0.50) | ATMMAPTALDH1A1PI4KAPIK3CG | |
| SCHEMBL9955387 | 0.74 | TDO2 (0.50) | TDO2IDO2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9954470 | 0.74 | HCAR1 (0.46) | ATMMAPTALDH1A1PDE7API4KA | |
| SCHEMBL10288659 | 0.73 | POLB (0.53) | IDO1TDO2IDO2ATMMAPT | |
| SCHEMBL9954343 | 0.72 | MAPT (0.49) | ATMMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL26856831 | 0.70 | TDO2 (0.77) | IDO1TDO2IDO2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |