Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954703 | 0.79 | DRD2 (0.44) | PLAAT3PLAAT5PLAAT2PLAAT4ESRRG | |
| SCHEMBL15675153 | 0.76 | KMT2A (0.50) | POLBMEN1KMT2AMAPT | |
| SCHEMBL9955074 | 0.76 | KMT2A (0.50) | POLBMEN1KMT2AMAPT | |
| SCHEMBL9955949 | 0.73 | MEN1 (0.38) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 | |
| SCHEMBL3709010 | 0.72 | HDAC1 (0.39) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 | |
| SCHEMBL3709009 | 0.72 | HDAC1 (0.39) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 | |
| SCHEMBL8331572 | 0.72 | NPC1 (0.61) | POLBESRRGNPC1RAB9AMAPT | |
| SCHEMBL9475067 | 0.71 | ESRRG (0.53) | ESRRGNPC1RAB9AMAPTHDAC2 | |
| SCHEMBL1864778 | 0.70 | ACACB (0.56) | RAB9A | |
| SCHEMBL1027242 | 0.69 | PLAAT3 (0.40) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655349-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087720-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |