Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709009 | 0.89 | HDAC1 (0.39) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL3709010 | 0.89 | HDAC1 (0.39) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9955344 | 0.79 | HSD11B1 (0.42) | HDAC6 | |
| SCHEMBL1845524 | 0.76 | HDAC1 (0.39) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL1845523 | 0.76 | HDAC1 (0.39) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL15674404 | 0.76 | ALOX5 (0.36) | MEN1KMT2AALOX5CHRM2CHRM3 | |
| SCHEMBL9955946 | 0.76 | ALOX5 (0.36) | MEN1KMT2AALOX5CHRM2CHRM3 | |
| SCHEMBL9954703 | 0.76 | DRD2 (0.44) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 | |
| SCHEMBL1846498 | 0.73 | TAAR1 (0.37) | MEN1KMT2ATAAR1TDP1HDAC1 | |
| SCHEMBL9954699 | 0.73 | NR1H2 (0.41) | MEN1KMT2ANPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655349-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087720-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |