Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1850432 | 0.84 | DRD2 (0.43) | DRD2DRD4OPRM1DRD3FDPS | |
| SCHEMBL9955077 | 0.79 | POLB (0.46) | MGLLPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL15674698 | 0.76 | SMN1; SMN2 (0.40) | OPRM1DRD3SMN1; SMN2 | |
| SCHEMBL10066477 | 0.76 | SMN1; SMN2 (0.40) | OPRM1DRD3SMN1; SMN2 | |
| SCHEMBL9955949 | 0.76 | MEN1 (0.38) | FDPSTAAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL3709009 | 0.75 | HDAC1 (0.39) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL3709010 | 0.75 | HDAC1 (0.39) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL1027242 | 0.74 | PLAAT3 (0.40) | DRD2DRD4OPRM1DRD3TAAR1 | |
| SCHEMBL4478781 | 0.74 | FDPS (0.61) | DRD2DRD4OPRM1DRD3FDPS | |
| SCHEMBL958756 | 0.70 | DRD2 (0.54) | DRD2DRD4OPRM1DRD3FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655349-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087720-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |