Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958617 | 0.90 | ABCG2 (0.51) | PTGESALOX5PLGNOX4HDAC3 | |
| SCHEMBL8442485 | 0.79 | POLH (0.64) | PLGNOX4ABCG2KDM4EMEN1 | |
| SCHEMBL3989919 | 0.78 | NOX4 (0.59) | ALOX5PLGNOX4HDAC6ABCG2 | |
| SCHEMBL17938761 | 0.74 | CYP3A4 (0.61) | ABCG2ABCB1KDM4EMEN1CYP3A4 | |
| SCHEMBL3404530 | 0.73 | AKR1B1 (0.64) | ALOX5PLGNOX4HDAC6ABCG2 | |
| SCHEMBL3173862 | 0.72 | ABCG2 (0.62) | ABCG2ABCB1ABCC1KDM4EMEN1 | |
| SCHEMBL23871902 | 0.72 | KDM4E (0.53) | PLGNOX4ABCG2ABCB1ABCC1 | |
| SCHEMBL31287228 | 0.70 | EPHX2 (0.63) | ALOX5NOX4HDAC6ABCG2ABCB1 | |
| SCHEMBL3985496 | 0.70 | MEN1 (0.64) | ALOX5PLGNOX4HDAC6ABCG2 | |
| SCHEMBL23278846 | 0.70 | ADORA3 (0.72) | ABCG2ABCB1ABCC1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468741-A1 | Novel quercetin derivatives, their preparation, pharmaceutical compositions containing them and their use | Bel/Novamann International s.r.o. (SK) | 2012-06-27 | — | — | EP | disclosed |