Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957959 | 1.00 | ALDH1A1 (0.40) | ALDH1A1HSD17B10HPGDBCL2L1TOP1 | |
| SCHEMBL17578935 | 0.77 | LRRK2 (0.39) | ALDH1A1HSD17B10HPGDBCL2L1MGLL | |
| SCHEMBL29354585 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4E | |
| SCHEMBL29941260 | 0.77 | CDC7 (0.35) | TOP1HTTLMNAMKNK1MKNK2 | |
| SCHEMBL28483770 | 0.76 | KDM4E (0.45) | ALDH1A1HSD17B10HPGDHTTLMNA | |
| SCHEMBL29955710 | 0.73 | NCOA1 (0.42) | ALDH1A1HSD17B10HPGDCHRNB2CHRNB4 | |
| SCHEMBL29709996 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDBCL2L1TOP1 | |
| SCHEMBL8526461 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDBCL2L1TOP1 | |
| SCHEMBL7647031 | 0.72 | PTGS2 (0.58) | ALDH1A1HSD17B10HPGDBCL2L1TOP1 | |
| SCHEMBL676668 | 0.71 | ALDH1A1 (0.57) | ALDH1A1HSD17B10HPGDBCL2L1TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2995616-B1 | HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2018-04-25 | — | — | EP | disclosed |
| EP-2818462-B1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMISCENT ELEMENT CONTAINING THESE AS COMPONENT | TOSOH CORP (JP) | 2017-11-08 | — | — | EP | disclosed |
| US-9624193-B2 | Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component | TOSOH CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |
| CN-106188053-A | A kind of electron transport material, preparation method and applications | 中节能万润股份有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-105754589-A | Electronic transmission material, preparation method thereof and organic electroluminescence device including electronic transmission material | 中节能万润股份有限公司 | 2016-07-13 | — | — | CN | disclosed |
| US-20160172598-A1 | HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG CHEM, LTD. (KR) | 2016-06-16 | — | — | US | disclosed |
| EP-2995616-A1 | HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG Chem, Ltd. (KR) | 2016-03-16 | — | — | EP | disclosed |
| US-20150329544-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | TOSOH CORPORATION (JP) | 2015-11-19 | — | — | US | disclosed |
| US-9120773-B2 | Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component | TOSOH CORPORATION (JP) | 2015-09-01 | — | — | US | disclosed |
| US-9102617-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-11 | — | — | US | disclosed |
| EP-2818462-A1 | Cyclic azine derivatives, processes for producing these, and organic electrolumiscent element containing these as component | TOSOH CORPORATION (JP) | 2014-12-31 | — | — | EP | disclosed |
| EP-2468731-B1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | TOSOH CORP (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
| US-20120214993-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | SAGAMI CHEMICAL RESEARCH INSTITUTE, (JP) | 2012-08-23 | — | — | US | disclosed |
| EP-2468731-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | Tosoh Corporation (JP) | 2012-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | RPS4X, RPS4Y1, MRPL21 | ALDH1A1 3775/4885HSD17B10 3692/4885HPGD 4414/4885 |
| US-20150329544-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | CPNE4, EPB41, AZI2 | ALDH1A1 267/4885HSD17B10 4514/4885HPGD 4413/4885 |
| US-20120214993-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | CPNE4, EPB41, AZI2 | ALDH1A1 267/4885HSD17B10 4514/4885HPGD 4413/4885 |
| US-20160172598-A1 | HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | CRY1, CRY2, PER2 | ALDH1A1 886/4885HSD17B10 1853/4885HPGD 3263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.