Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10828233 | 0.87 | CA12 (0.44) | TSHRMAPTALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL16447333 | 0.87 | LMNA (0.33) | TSHRLMNAMAPTALDH1A1PMP22 | |
| SCHEMBL897358 | 0.84 | — | — | |
| SCHEMBL10827955 | 0.83 | CA12 (0.48) | TSHRALDH1A1TP53TDP1NPC1 | |
| SCHEMBL1950012 | 0.82 | HDAC1 (0.35) | TSHRLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10828191 | 0.80 | CA12 (0.44) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL10828032 | 0.78 | CA12 (0.45) | TSHRLMNAMAPTALDH1A1PMP22 | |
| SCHEMBL559019 | 0.78 | PIN1 (0.33) | — | |
| SCHEMBL571432 | 0.75 | TSHR (0.35) | TSHRLMNAMAPTALDH1A1PMP22 | |
| SCHEMBL8711678 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129243-B1 | NON-AQUEOUS ELECTROCHEMICAL CELL | HONEYWELL INC. (US) | 1988-10-19 | — | — | EP | claimed |
| US-4439503-A | N,N-DIHALOCARBAMATE | HONEYWELL INC. (US) | 1984-03-27 | — | — | US | claimed |
| US-12637492-B2 | Peptide inhibitors of focal adhesion kinase activity and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-05-26 | — | — | US | disclosed |
| US-12521386-B2 | Small molecule inhibitors of the androgen receptor activity and/or expression and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-01-13 | — | — | US | disclosed |
| US-12509468-B2 | Quindoline compounds and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2025-12-30 | — | — | US | disclosed |
| US-20250189527-A1 | COMPOSITIONS AND METHODS FOR DETECTING, PREDICTING RISK OF DEVELOPING, AND TREATING LEPTOMENINGEAL DISEASE | DUKE UNIVERSITY | 2025-06-12 | — | — | US | disclosed |
| CN-118271237-A | Substituted phenol derivative and use thereof | 成都麻沸散医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114026082-B | Pyridin-3-yl derivatives | 爱杜西亚药品有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118076607-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| US-11944626-B2 | Small molecule inhibitors of ALDH and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-04-02 | — | — | US | disclosed |
| CN-112236424-B | Alkoxy-substituted pyridinyl derivatives | 爱杜西亚药品有限公司 | 2024-03-15 | — | — | CN | disclosed |
| US-4751161-A | CONTAINING HALOCARBON CATHODE DEPOLARIZER AND CARBON CATHODE WITH COBALT, NICKEL, OR IRON MALROCYCLIC CATALYST | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1988-06-14 | — | — | US | disclosed |
| US-4592869-A | Selective acylation process | AKTIEBOLAGET LEO (SE) | 1986-06-03 | — | — | US | disclosed |
| EP-0138153-A2 | A selective acylation process | AB LEO (SE) | 1985-04-24 | — | — | EP | disclosed |
| EP-0129243-A1 | Non-aqueous electrochemical cell | HONEYWELL INC. (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4439503-A | N,N-DIHALOCARBAMATE | HONEYWELL INC. (US) | 1984-03-27 | — | — | US | disclosed |
| US-4177289-A | FUNGICIDES, HERBICIDES, BACTERICIDES | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4171449-A | Addition of N,N-dichloro-N-acyl compounds to conjugated dienes and bis-N-chlorocrotyl carbamate products therefrom | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-10-16 | — | — | US | disclosed |
| US-4170608-A | REDUCTION, PESTICIDES | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-10-09 | — | — | US | disclosed |
| US-4146557-A | CHLORINATION, DECHLORINATION, ALKYLATION | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12509468-B2 | Quindoline compounds and uses thereof | TPD52L2, BRDT, RECQL | TSHR 2558/4885LMNA 2504/4885MAPT 1757/4885 |
| US-11944626-B2 | Small molecule inhibitors of ALDH and uses thereof | ALDH2, ALDH1A1, ALDH3A1 | TSHR 3677/4885LMNA 4748/4885MAPT 2448/4885 |
| US-12637492-B2 | Peptide inhibitors of focal adhesion kinase activity and uses thereof | PTK2, ILK, FPR2 | TSHR 4402/4885LMNA 1096/4885MAPT 3761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.