Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9962934 | 0.90 | KMT2A (0.37) | ITGA1PTPN1MAPTALDH1A1POLB | |
| SCHEMBL218851 | 0.86 | HTT (0.39) | HTTMAPTALDH1A1POLBKMT2A | |
| SCHEMBL9962920 | 0.86 | MAPT (0.38) | ITGA1PTPN1HTTCYP1A2CYP2C9 | |
| SCHEMBL9614315 | 0.84 | HTT (0.39) | HTTMAPTALDH1A1POLBKMT2A | |
| SCHEMBL19939980 | 0.81 | HTT (0.35) | HTTCYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL13039213 | 0.80 | ITGA1 (0.38) | ITGA1CYP2C9MAPTALDH1A1POLB | |
| SCHEMBL9962926 | 0.79 | KMT2A (0.42) | HTTMAPTALDH1A1POLBKMT2A | |
| SCHEMBL13039218 | 0.76 | HTT (0.32) | HTTALDH1A1KMT2AKDM4EPTGS2 | |
| SCHEMBL29948312 | 0.74 | HTT (0.40) | HTTCYP2C9CYP2C19MAPTALDH1A1 | |
| SCHEMBL168580 | 0.74 | HTT (0.40) | HTTCYP2C9CYP2C19MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202731-B2 | HPTS-mono and bis Cys-MA polymerizable fluorescent dyes for use in analyte sensors | GLUMETRICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-8202731-B2 | HPTS-mono and bis Cys-MA polymerizable fluorescent dyes for use in analyte sensors | GLUMETRICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20100279424-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100279424-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-7824918-B2 | HPTS-Mono and BIS Cys-Ma polymerizable fluorescent dyes for use in analyte sensors | GLUMETRICS, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| US-7824918-B2 | HPTS-Mono and BIS Cys-Ma polymerizable fluorescent dyes for use in analyte sensors | GLUMETRICS, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| US-20090061528-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090061528-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279424-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | PTMS, PFAS, HMBS | ITGA1 2575/4885PTPN1 1085/4885HTT 1400/4885 |
| US-20090061528-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | PTMS, PFAS, HMBS | ITGA1 2575/4885PTPN1 1085/4885HTT 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.