SCHEMBL9962934

SCHEMBL9962934

CC(=O)Oc1cc(S(=O)(=O)Oc2ccc(S(=O)(=O)Cl)cc2)c2ccc3c(S(=O)(=O)Cl)cc(S(=O)(=O)Cl)c4ccc1c2c43

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.37
MAPT P10636 5/20 0.37
POLB P06746 4/20 0.37
PKM P14618 2/20 0.37
PTPN1 P18031 1/20 0.36
GAA P10253 1/20 0.35
MEN1 O00255 3/20 0.34
ALDH1A1 P00352 2/20 0.34
RECQL P46063 1/20 0.33
LMNA P02545 1/20 0.33
PTGS2 P35354 2/20 0.32
ITGA1 P56199 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9962933 0.90 ITGA1 (0.37) KMT2AMAPTPOLBPKMPTPN1
SCHEMBL218851 0.85 HTT (0.39) KMT2AMAPTPOLBPKMGAA
SCHEMBL9614315 0.83 HTT (0.39) KMT2AMAPTPOLBPKMGAA
SCHEMBL19939980 0.80 HTT (0.35) KMT2AMAPTPOLBPKMGAA
SCHEMBL9962920 0.76 MAPT (0.38) KMT2AMAPTPOLBPTPN1GAA
SCHEMBL9962926 0.76 KMT2A (0.42) KMT2AMAPTPOLBGAAMEN1
SCHEMBL13039218 0.75 HTT (0.32) KMT2AALDH1A1PTGS2KDM4E
SCHEMBL381650 0.75 HTT (0.39) KMT2AMAPTPOLBPKMGAA
SCHEMBL381649 0.73 KMT2A (0.41) KMT2AMAPTPOLBPKMPTPN1
SCHEMBL29948531 0.73 KMT2A (0.41) KMT2AMAPTPOLBPKMPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8202731-B2 HPTS-mono and bis Cys-MA polymerizable fluorescent dyes for use in analyte sensors GLUMETRICS, INC. (US) 2012-06-19 US disclosed
US-8202731-B2 HPTS-mono and bis Cys-MA polymerizable fluorescent dyes for use in analyte sensors GLUMETRICS, INC. (US) 2012-06-19 US disclosed
US-20100279424-A1 HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS GLUMETRICS INC. (US) 2010-11-04 US disclosed
US-20100279424-A1 HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS GLUMETRICS INC. (US) 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279424-A1 HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS PTMS, PFAS, HMBS KMT2A 3629/4885MAPT 3420/4885POLB 3753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.