SCHEMBL9965745

SCHEMBL9965745

CC1(C)c2ccccc2-c2cc3c(cc21)-c1c(cc(-c2ccc(N(c4ccccc4)c4ccccc4)cc2)c2ccccc12)C3(C)C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PDK2 Q15119 1/20 0.32
MLNR O43193 1/20 0.30
NR1I2 O75469 1/20 0.30
CHRM2 P08172 1/20 0.30
ADRB1 P08588 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL358382 0.93 ALDH1A1 (0.33) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL16219604 0.93 PDK2 (0.36) PDK2
SCHEMBL15505775 0.91 PDK2 (0.34) PDK2GPR84
SCHEMBL12952448 0.91 ACHE (0.33) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL15505887 0.90 ALDH1A1 (0.31) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL11914332 0.90 KDM4E (0.33) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL15505852 0.90 ALDH1A1 (0.33) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL18334010 0.89 PDK2 (0.31) PDK2
SCHEMBL15505876 0.89 PDK2 (0.36) PDK2
SCHEMBL15505857 0.89 MEN1 (0.31) ALDH1A1MAPTTDP1L3MBTL1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3559078-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-25 EP disclosed
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 US disclosed
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 US disclosed
US-20230108986-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-04-06 US disclosed
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-07-12 US disclosed
US-20220199908-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2022-06-23 US disclosed
US-20210367155-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-11-25 US disclosed
EP-3571264-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-11-24 EP disclosed
WO-2012084114-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2012-06-28 WO disclosed
WO-2012079673-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2012-06-21 WO disclosed
WO-2012045384-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-04-12 WO disclosed
WO-2012016630-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-02-09 WO disclosed
WO-2011160757-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-12-29 WO disclosed
WO-2011157346-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-12-22 WO disclosed
WO-2011116869-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-09-29 WO disclosed
WO-2011110262-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2011-09-15 WO disclosed
WO-2011054442-A2 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-05-12 WO disclosed
WO-2011035836-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210367155-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES EPB41, EPB41L2, MCM4 KDM4E 852/4885ALDH1A1 73/4885CYP1A2 441/4885
US-11737352-B2 Materials for organic electroluminescent devices EPB41, EPB41L2, MCM4 KDM4E 852/4885ALDH1A1 73/4885CYP1A2 441/4885
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices PKD1, PIEZO1, AQP1 KDM4E 4609/4885ALDH1A1 26/4885CYP1A2 852/4885
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES SELE, EPHA6, EPX KDM4E 2986/4885ALDH1A1 1837/4885CYP1A2 2239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.