Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CCR2 | P41597 | 4/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931009 | 0.85 | CCR2 (0.62) | TERTCCR2 | |
| SCHEMBL9967989 | 0.75 | CYP2C9 (0.53) | ALDH1A1SMN1; SMN2CCR2MAPT | |
| SCHEMBL9968076 | 0.70 | CCR2 (0.61) | CCR2 | |
| SCHEMBL15571296 | 0.70 | MAPT (0.59) | TERTALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL7590523 | 0.69 | LMNA (0.69) | ALDH1A1MAPTPOLB | |
| SCHEMBL9931481 | 0.68 | CCR2 (0.77) | CCR2 | |
| SCHEMBL9931430 | 0.66 | CCR2 (0.62) | CCR2 | |
| SCHEMBL9967885 | 0.66 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5698738 | 0.66 | PTGS2 (0.65) | TERTALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL20846589 | 0.66 | TERT (0.58) | TERTALDH1A1SMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082633-A1 | NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-21 | — | — | WO | disclosed |