Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968558 | 0.86 | BRD4 (0.47) | HSD17B1HSD17B2KDM1A | |
| SCHEMBL4402499 | 0.84 | HPGDS (0.46) | HSD17B1HSD17B2MAP4K4NPC1HPGDS | |
| SCHEMBL12973163 | 0.79 | HSD17B1 (0.59) | HSD17B1HSD17B2MAP4K4KDM1ANPC1 | |
| SCHEMBL13910991 | 0.79 | HSD17B1 (0.63) | HSD17B1HSD17B2NPC1HPGDSKDM4E | |
| SCHEMBL12957239 | 0.77 | HSD17B1 (0.67) | HSD17B1HSD17B2MAP4K4IRAK4NPC1 | |
| SCHEMBL4402515 | 0.76 | HSD17B1 (0.61) | HSD17B1HSD17B2MAP4K4KDM1ACYP3A4 | |
| SCHEMBL4406991 | 0.76 | HSD17B1 (0.51) | HSD17B1HSD17B2MAP4K4KDM1ARAB9A | |
| SCHEMBL12129605 | 0.75 | HSD17B1 (0.59) | HSD17B1HSD17B2CYP3A4CYP2A6MEN1 | |
| SCHEMBL9968559 | 0.75 | HSD17B1 (0.64) | HSD17B1HSD17B2KDM1AIRAK4NPC1 | |
| SCHEMBL4400277 | 0.75 | HSD17B1 (0.50) | HSD17B1HSD17B2MAP4K4KDM1ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
| US-8106193-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-01-31 | — | — | US | disclosed |
| US-20100317851-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157681-A1 | LUMINOPHORES | PPOX, CRY1, MPO | HSD17B1 1397/4885HSD17B2 1757/4885MAP4K4 4128/4885 |
| US-20100317851-A1 | LUMINOPHORES | PPOX, CRY1, MPO | HSD17B1 1833/4885HSD17B2 1857/4885MAP4K4 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.