Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18956343 | 0.85 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2L3MBTL1LMNAUSP2 | |
| SCHEMBL1458948 | 0.83 | PKM (0.67) | ALDH1A1SMN1; SMN2L3MBTL1LMNAUSP2 | |
| SCHEMBL13681851 | 0.81 | CYP2C9 (0.56) | ALDH1A1LMNAUSP2GAAMAPK1 | |
| SCHEMBL24359465 | 0.76 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2L3MBTL1LMNAUSP2 | |
| SCHEMBL15480444 | 0.75 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2LMNAUSP2GAA | |
| SCHEMBL14255024 | 0.75 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2LMNAUSP2GAA | |
| SCHEMBL9975566 | 0.75 | TRPV1 (0.71) | ALDH1A1SMN1; SMN2TSHRGAANPC1 | |
| SCHEMBL18956279 | 0.75 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2L3MBTL1LMNAUSP2 | |
| SCHEMBL4687548 | 0.75 | FFAR2 (0.74) | ALDH1A1SMN1; SMN2L3MBTL1LMNAUSP2 | |
| SCHEMBL21533450 | 0.74 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2L3MBTL1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202893-B2 | Cannabinergic lipid ligands | UNIVERSITY OF CONNECTICUT (US) | 2012-06-19 | — | — | US | disclosed |
| US-8202893-B2 | Cannabinergic lipid ligands | UNIVERSITY OF CONNECTICUT (US) | 2012-06-19 | — | — | US | disclosed |
| US-20090163557-A1 | Cannabinergic Lipid Ligands | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-06-25 | — | — | US | disclosed |
| US-20090163557-A1 | Cannabinergic Lipid Ligands | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163557-A1 | Cannabinergic Lipid Ligands | FAAH, FAAH2, CNR2 | ALDH1A1 2311/4885SMN1; SMN2 3576/4885L3MBTL1 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.