Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.57 |
| ▸ | CA1 | P00915 | 13/20 | 0.57 |
| ▸ | CA12 | O43570 | 12/20 | 0.57 |
| ▸ | CA9 | Q16790 | 12/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.57 |
| ▸ | CA7 | P43166 | 4/20 | 0.57 |
| ▸ | CA6 | P23280 | 2/20 | 0.57 |
| ▸ | CA5A | P35218 | 2/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL570163 | 0.80 | CA2 (0.68) | CA2CA1CA12CA9CA14 | |
| Ethyl Benzoate SCHEMBL29187656 | 0.80 | LMNA (0.64) | CA2CA1CA12CA9CA14 | |
| Sulfanilamide SCHEMBL28520704 | 0.80 | CA2 (0.74) | CA2CA1CA12CA9CA14 | |
| Sulfanilamide SCHEMBL419065 | 0.80 | CA2 (0.74) | CA2CA1CA12CA9CA14 | |
| Sulfanilamide SCHEMBL28552204 | 0.79 | CA2 (0.61) | CA2CA1CA12CA9CA14 | |
| Sulfanilamide SCHEMBL2215151 | 0.78 | CA2 (0.77) | CA2CA1CA12CA9CA14 | |
| Sulfanilamide SCHEMBL20567505 | 0.78 | CA2 (0.77) | CA2CA1CA12CA9CA14 | |
| Sulfanilamide SCHEMBL28201481 | 0.78 | CA2 (0.85) | CA2CA1CA12CA9CA14 | |
| Aniline SCHEMBL27371840 | 0.77 | ALOX15 (0.60) | TSHRALOX15MEN1KMT2ALMNA | |
| Sulfanilamide SCHEMBL27623151 | 0.76 | CA2 (0.74) | CA2CA1CA12CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8779179-B2 | Synthesis of silyl acetylenes | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130150606-A1 | SYNTHESIS OF SILYL ACETYLENES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2011149735-A1 | SYNTHESIS OF SILYL ACETYLENES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150606-A1 | SYNTHESIS OF SILYL ACETYLENES | TST, ACE, ACE2 | CA2 1272/4885CA1 577/4885CA12 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.