Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 4/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968586 | 0.88 | PLA2G4A (0.53) | PLA2G4AALDH1A1ATMTNFMAPT | |
| SCHEMBL30396580 | 0.82 | F2 (0.45) | ALDH1A1ATMTNFMAPTLMNA | |
| SCHEMBL3689068 | 0.82 | F2 (0.45) | ALDH1A1ATMTNFMAPTLMNA | |
| SCHEMBL20037274 | 0.81 | ALDH1A1 (0.50) | ALDH1A1ATMTNFKDM4E | |
| SCHEMBL20037218 | 0.81 | TDP1 (0.53) | ALDH1A1ATMKRASMAPTLMNA | |
| SCHEMBL29138523 | 0.81 | MTNR1A (0.56) | ALDH1A1ATMTNFMAPTLMNA | |
| SCHEMBL1666483 | 0.81 | NTSR1 (0.52) | ALDH1A1ATMTNFMAPTLMNA | |
| SCHEMBL4483940 | 0.81 | ATM (0.43) | ALDH1A1ATMTNFMAPTLMNA | |
| SCHEMBL4485443 | 0.81 | NTSR1 (0.52) | ALDH1A1ATMKRASLMNAMEN1 | |
| SCHEMBL19777848 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ATMTNFMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |