Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171839 | 0.81 | CYP1A2 (0.47) | MRGPRX4ACHESLC6A3SLC6A2SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL27831764 | 0.79 | CYP1A2 (0.46) | MRGPRX4ACHESLC6A3SLC6A2SLC6A4 | |
| SCHEMBL13130874 | 0.79 | MRGPRX4 (0.40) | MRGPRX4ACHEHDAC1HDAC6NISCH | |
| SCHEMBL257852 | 0.77 | SOS1 (0.50) | MRGPRX4ACHEHDAC1HDAC6SLC6A4 | |
| SCHEMBL450533 | 0.77 | MRGPRX4 (0.39) | MRGPRX4ACHEHDAC1HDAC6NISCH | |
| SCHEMBL9979922 | 0.77 | SOS1 (0.44) | SLC6A4ALDH1A1L3MBTL1CYP1A1CYP1A2 | |
| SCHEMBL14220258 | 0.76 | NQO1 (0.52) | MRGPRX4KDM4ENPC1ALDH1A1L3MBTL1 | |
| SCHEMBL900910 | 0.76 | PDE2A (0.47) | MRGPRX4KDM4EGAAMAPT | |
| SCHEMBL21271958 | 0.76 | MRGPRX4 (0.38) | MRGPRX4ACHEHDAC1HDAC6NISCH | |
| SCHEMBL11963662 | 0.76 | ALDH1A1 (0.44) | MRGPRX4HDAC1HDAC6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938464-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9612445-B2 | Lens element | MERCK PATENT GMBH (DE) | 2017-04-04 | — | — | US | disclosed |
| US-20170002290-A1 | ELECTRO-RHEOLOGICAL FLUID AND HAPTIC DEVICE | MERCK PATENT GMBH (DE) | 2017-01-05 | — | — | US | disclosed |
| US-20160326436-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-11-10 | — | — | US | disclosed |
| US-20150301344-A1 | LENS ELEMENT | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-8168083-B2 | Electro-optical light control element, electro-optical display and control medium | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-7922934-B2 | s-Indacene and indeno[5,6-d][1,3]dioxol-derivatives and use thereof as components of liquid-crystal mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-04-12 | — | — | US | disclosed |
| US-7914859-B2 | Light modulation media, use in particular for electrooptic displays which are operated at a temperature at which the mesogenic modulation media are in an optically isotropic phase, preferably in a blue phase; reduced operating voltage, reduced temperature dependency of operating voltage, reliability | MERCK PATENT GMBH (DE) | 2011-03-29 | — | — | US | disclosed |
| US-20100188630-A1 | ELECTRO-OPTICAL LIGHT CONTROL ELEMENT, ELECTRO-OPTICAL DISPLAY AND CONTROL MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20100155662-A1 | S-INDACENE AND INDENO[5,6-D][1,3]DIOXOL-DERIVATIVES AND USE THEREOF AS COMPONENTS OF LIQUID-CRYSTAL MIXTURES | MERCK PATENT GESELLSCHAFT (DE) | 2010-06-24 | — | — | US | disclosed |
| US-7691455-B2 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2010-04-06 | — | — | US | disclosed |
| US-7563491-B2 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2009-07-21 | — | — | US | disclosed |
| US-7553522-B2 | LC-mixtures with low frequency dependence for TFT-displays | MERCK PATENT GMBH (DE) | 2009-06-30 | — | — | US | disclosed |
| US-7482044-B2 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2009-01-27 | — | — | US | disclosed |
| US-7445819-B2 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2008-11-04 | — | — | US | disclosed |
| US-20080124492-A1 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GMBH | 2008-05-29 | — | — | US | disclosed |
| US-20080116419-A1 | Mesogenic Compounds, Liquid Crystal Medium and Liquid Crystal Display | MERCK PATENT GMBH (DE) | 2008-05-22 | — | — | US | disclosed |
| US-20070235688-A1 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GESELLSCHAFT | 2007-10-11 | — | — | US | disclosed |
| US-20070034829-A1 | liquid crystalline medium comprises at least one strongly polar two-ring compound containing at least one fluorine group and two benezne rings; liquid-crystalline medium has a dielectric relaxation frequency of more than 200 kHz at a temperature of 0 degrees C.; use in active matrix displays | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100155662-A1 | S-INDACENE AND INDENO[5,6-D][1,3]DIOXOL-DERIVATIVES AND USE THEREOF AS COMPONENTS OF LIQUID-CRYSTAL MIXTURES | IPO5, SFXN3, SFXN1 | MRGPRX4 3437/4885ACHE 2650/4885HDAC1 4790/4885 |
| US-20080116419-A1 | Mesogenic Compounds, Liquid Crystal Medium and Liquid Crystal Display | CRY1, CRY2, IK | MRGPRX4 844/4885ACHE 955/4885HDAC1 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.