Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6420390 | 0.97 | BBOX1 (0.48) | BBOX1KDM4ESLC18A3TP53LMNA | |
| SCHEMBL3817323 | 0.97 | — | — | |
| Iodide SCHEMBL25405847 | 0.94 | KDM4E (0.50) | BBOX1KDM4ESLC18A3TP53LMNA | |
| Bromide SCHEMBL31611905 | 0.94 | BBOX1 (0.46) | BBOX1KDM4ESLC18A3TP53LMNA | |
| SCHEMBL1920897 | 0.94 | KDM4E (0.50) | BBOX1KDM4ESLC18A3TP53LMNA | |
| SCHEMBL10256521 | 0.94 | KDM4E (0.50) | BBOX1KDM4ESLC18A3TP53LMNA | |
| Bromide SCHEMBL338899 | 0.92 | KDM4E (0.48) | BBOX1KDM4ESLC18A3TP53LMNA | |
| Iodide SCHEMBL14778907 | 0.92 | KDM4E (0.54) | BBOX1KDM4ESLC18A3TP53LMNA | |
| SCHEMBL25557911 | 0.92 | — | — | |
| SCHEMBL9987682 | 0.87 | BBOX1 (0.42) | BBOX1KDM4ESLC18A3TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8961656-B2 | Gas hydrate inhibitor and method of inhibiting gas hydrate formation | KOREA INSTITUTE OF ENERGY RESEARCH (KR) | 2015-02-24 | — | — | US | claimed |
| US-20130112923-A1 | Composition and Method for Inhibiting Gas Hydrate Formation | KOREA INSTITUTE OF ENERGY RESEARCH (KR) | 2013-05-09 | — | — | US | claimed |
| US-20110319682-A1 | Gas Hydrate Inhibitor and Method of Inhibiting Gas Hydrate Formation | KOREA INSTITUTE OF ENERGY RESEARCH (KR) | 2011-12-29 | — | — | US | claimed |
| EP-2834251-B1 | IONIC COMPOUNDS HAVING A SILYLOXY GROUP | HYDRO QUEBEC (CA) | 2019-11-13 | — | — | EP | disclosed |
| US-9969757-B2 | Ionic compounds having a silyloxy group | HYDRO-QUEBEC (CA) | 2018-05-15 | — | — | US | disclosed |
| US-9748605-B2 | Sulfur-containing additives for electrochemical or optoelectronic devices | BASF SE (DE) | 2017-08-29 | — | — | US | disclosed |
| EP-2748145-B1 | SULFUR-CONTAINING ADDITIVES FOR ELECTROCHEMICAL OR OPTOELECTRONIC DEVICES | BASF SE (DE) | 2016-10-19 | — | — | EP | disclosed |
| US-9228075-B2 | Composition and method for inhibiting gas hydrate formation | KOREA INSTITUTE OF ENERGY RESEARCH (KR) | 2016-01-05 | — | — | US | disclosed |
| US-20150093655-A1 | IONIC COMPOUNDS HAVING A SILYLOXY GROUP | HYDRO-QUEBEC (CA) | 2015-04-02 | — | — | US | disclosed |
| US-8961656-B2 | Gas hydrate inhibitor and method of inhibiting gas hydrate formation | KOREA INSTITUTE OF ENERGY RESEARCH (KR) | 2015-02-24 | — | — | US | disclosed |
| EP-2834251-A1 | IONIC COMPOUNDS HAVING A SILYLOXY GROUP | Hydro-Québec (CA) | 2015-02-11 | — | — | EP | disclosed |
| US-20140193707-A1 | SULFUR-CONTAINING ADDITIVES FOR ELECTROCHEMICAL OR OPTOELECTRONIC DEVICES | BASF SE (DE) | 2014-07-10 | — | — | US | disclosed |
| EP-2748145-A1 | SULFUR-CONTAINING ADDITIVES FOR ELECTROCHEMICAL OR OPTOELECTRONIC DEVICES | BASF SE (DE) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013149349-A1 | IONIC COMPOUNDS HAVING A SILYLOXY GROUP | HYDRO-QUéBEC (CA) | 2013-10-10 | — | — | WO | disclosed |
| US-20130112923-A1 | Composition and Method for Inhibiting Gas Hydrate Formation | KOREA INSTITUTE OF ENERGY RESEARCH (KR) | 2013-05-09 | — | — | US | disclosed |
| WO-2013026854-A1 | SULFUR-CONTAINING ADDITIVES FOR ELECTROCHEMICAL OR OPTOELECTRONIC DEVICES | BASF SE (DE) | 2013-02-28 | — | — | WO | disclosed |
| US-20110319682-A1 | Gas Hydrate Inhibitor and Method of Inhibiting Gas Hydrate Formation | KOREA INSTITUTE OF ENERGY RESEARCH (KR) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150093655-A1 | IONIC COMPOUNDS HAVING A SILYLOXY GROUP | EPCAM, ILK, VIM | CHRM2 2032/4885CHRM1 1849/4885CHRM3 775/4885 |
| US-20110319682-A1 | Gas Hydrate Inhibitor and Method of Inhibiting Gas Hydrate Formation | HDHD5, AQP1, API5 | CHRM2 4426/4885CHRM1 4576/4885CHRM3 3474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.