Naphthalene

Naphthalene

SCHEMBL998754

NNC(=O)NN.NNC(=O)NN.c1ccc2ccccc2c1

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
GAA P10253 5/20 0.47
TDP1 Q9NUW8 2/20 0.47
MEN1 O00255 1/20 0.47
MITF O75030 1/20 0.47
KMT2A Q03164 1/20 0.47
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
ALDH1A1 P00352 6/20 0.45
CYP2A6 P11509 1/20 0.44
ALOX12 P18054 1/20 0.44
KDM4E B2RXH2 4/20 0.44
MAPK1 P28482 1/20 0.44
CTSD P07339 1/20 0.43
NPC1 O15118 3/20 0.42
RAB9A P51151 2/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CYP3A4 P08684 2/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL28096488 1.00 MAPT (0.47) MAPTGAATDP1MEN1MITF
Pyrene SCHEMBL28003052 0.82 ALDH1A1 (0.52) MAPTGAATDP1MEN1MITF
Biphenyl SCHEMBL998756 0.81 MGLL (0.48) MAPTGAAMEN1KMT2AALDH1A1
Naphthalene SCHEMBL27875545 0.81 NAPRT (0.46) MAPTGAATDP1MEN1MITF
Biphenyl SCHEMBL11066477 0.81 MGLL (0.48) MAPTGAAMEN1KMT2AALDH1A1
Benzene SCHEMBL27433216 0.78 CYP1A2 (0.44) MEN1KMT2AALDH1A1KDM4ECTSD
Benzoic Acid SCHEMBL14938995 0.77 TSHR (0.67) MAPTTDP1MEN1KMT2AALDH1A1
Toluene SCHEMBL27502728 0.77 LMNA (0.52) MAPTMEN1KMT2AALDH1A1ALOX12
Benzofuran SCHEMBL28839906 0.77 MAOB (0.41) MAPTGAATDP1MEN1MITF
SCHEMBL8596702 0.77 RAB9A (0.71) MAPTGAATDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2330155-B1 POLYACETAL RESIN COMPOSITION, RESIN MOLDED ARTICLE, AND METHOD AND AGENT FOR IMPROVING POLYACETAL RESIN RAW MATERIAL COMPOSITION MITSUBISHI ENG PLASTICS CORP (JP) 2016-08-24 EP claimed
US-7868102-B2 Method for producing a film of an aromatic amide oxadiazole polymer containing an oxadiazole structure and the film so produced TORAY INDUSTRIES, INC. (JP) 2011-01-11 US disclosed
EP-1602680-B1 AROMATIC POLYMER, FILM, ELECTROLYTE MEMBRANE AND SEPARATOR TORAY INDUSTRIES (JP) 2010-12-22 EP disclosed
EP-2258746-A2 A method for producing an aromatic polymer, film, electrolyte membrane and separator Toray Industries, Inc. (JP) 2010-12-08 EP disclosed
US-20100016521-A1 Method for producing a film of an aromatic amide oxadiazole polymer containing an oxadiazole structure and the film so produced MORIYAMA HIDEKI 2010-01-21 US disclosed
US-20090182171-A1 Compound having oxadiazole structure and a dehydration-cyclization method for producing the same MORIYAMA HIDEKI 2009-07-16 US disclosed
US-7511112-B2 Aromatic polymer, film, electrolyte membrane and separator TORAY INDUSTRIES, INC. (JP) 2009-03-31 US disclosed
US-20060204812-A1 Aromatic polymer, film, electrolyte membrane and separator MORIYAMA HIDEKI 2006-09-14 US disclosed
EP-1602680-A1 AROMATIC POLYMER, FILM, ELECTROLYTE MEMBRANE AND SEPARATOR TORAY INDUSTRIES, INC. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182171-A1 Compound having oxadiazole structure and a dehydration-cyclization method for producing the same OGFOD1, ODC1, OTC MAPT 3674/4885GAA 1002/4885TDP1 3801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.