Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988702 | 0.95 | PTGS2 (0.58) | PTGS2RXFP1KDM5BKDM4ERXRA | |
| SCHEMBL9989269 | 0.91 | PTGS2 (0.54) | PTGS2RXFP1KMT2AMEN1KDM4E | |
| SCHEMBL9988387 | 0.83 | DRD4 (0.49) | PTGS2KDM5BKDM4ESMN1; SMN2POLB | |
| SCHEMBL9989347 | 0.82 | RXRA (0.49) | PTGS2RXRARXRBRXRG | |
| SCHEMBL9988392 | 0.81 | MC4R (0.57) | PTGS2KMT2ARXRARXRBRXRG | |
| SCHEMBL9989304 | 0.80 | RXRA (0.52) | PTGS2KMT2ARXRARXRBRXRG | |
| SCHEMBL9989355 | 0.80 | MALT1 (0.62) | PTGS2KDM4ERXRARXRBRXRG | |
| SCHEMBL9988457 | 0.80 | PTGS2 (0.44) | PTGS2KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL9988533 | 0.78 | LMNA (0.49) | PTGS2KDM5BKDM4EGAASMN1; SMN2 | |
| SCHEMBL3234436 | 0.77 | CNR1 (0.54) | PTGS2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |