Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988404 | 0.91 | PTGS2 (0.59) | PTGS2RXFP1KMT2AMEN1GAA | |
| SCHEMBL9988702 | 0.86 | PTGS2 (0.58) | PTGS2RXFP1POLBKDM4E | |
| SCHEMBL9988526 | 0.84 | RXRA (0.45) | PTGS2KDM4E | |
| SCHEMBL9988387 | 0.80 | DRD4 (0.49) | PTGS2SMN1; SMN2POLBKDM4E | |
| SCHEMBL9990181 | 0.80 | MALT1 (0.53) | PTGS2GAA | |
| SCHEMBL9989490 | 0.80 | RXRA (0.50) | PTGS2KMT2AMEN1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9466114 | 0.77 | RXRA (0.68) | PTGS2 | |
| SCHEMBL9990308 | 0.77 | RXRA (0.47) | PTGS2KMT2AGAATDP1 | |
| SCHEMBL9993178 | 0.77 | RXRA (0.47) | PTGS2RXFP1KMT2AMEN1GAA | |
| SCHEMBL9989653 | 0.77 | RXRA (0.53) | PTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |