Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.47 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.47 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RPA1 | P27694 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CCKAR | P32238 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988392 | 0.93 | MC4R (0.57) | MC4RRXRARXRBRXRGFABP3 | |
| SCHEMBL9989656 | 0.88 | MALT1 (0.53) | RXRARXRBRXRGTP53LMNA | |
| SCHEMBL9989046 | 0.86 | TP53 (0.50) | RXRARXRBRXRGTP53LMNA | |
| SCHEMBL9990141 | 0.85 | RXRA (0.51) | RXRARXRBRXRGTP53LMNA | |
| SCHEMBL9999143 | 0.85 | RXRA (0.69) | RXRARXRBRXRGFABP3FABP4 | |
| SCHEMBL9988567 | 0.84 | MALT1 (0.55) | RXRARXRBRXRGTP53LMNA | |
| SCHEMBL9988533 | 0.84 | LMNA (0.49) | RXRARXRBRXRGTP53LMNA | |
| SCHEMBL9989576 | 0.84 | MALT1 (0.52) | RXRARXRBRXRGTP53LMNA | |
| SCHEMBL9990250 | 0.83 | RXRA (0.51) | RXRARXRBRXRGTP53LMNA | |
| SCHEMBL9988490 | 0.83 | LMNA (0.49) | RXRARXRBRXRGTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |