Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144462 | 0.76 | TNF (0.44) | PPARGPPARATNFMEN1MAPT | |
| SCHEMBL9989292 | 0.75 | CYP17A1 (0.39) | TNFCLK2CLK4 | |
| SCHEMBL9989533 | 0.75 | PPARG (0.37) | PPARGPPARAS1PR1 | |
| SCHEMBL6274844 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL9988687 | 0.72 | XDH (0.39) | PPARGPPARAS1PR1DHODHMEN1 | |
| SCHEMBL2265426 | 0.71 | GSTP1 (0.46) | EDNRBEDNRA | |
| SCHEMBL9989324 | 0.71 | GABRA1 (0.43) | PPARGPPARAS1PR1DHODHMEN1 | |
| SCHEMBL6599296 | 0.70 | MEN1 (0.44) | MEN1POLBMAPTKMT2AXDH | |
| SCHEMBL9989326 | 0.70 | TNF (0.42) | PPARGPPARAS1PR1TNFDHODH | |
| SCHEMBL2268337 | 0.69 | CYP1A2 (0.41) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011163610-A2 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-29 | — | — | WO | disclosed |