Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989594 | 0.86 | NPC1 (0.49) | NPC1ALDH1A1SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9988491 | 0.84 | ALDH1A1 (0.49) | NPC1ALDH1A1SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9990127 | 0.84 | CA1 (0.44) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9989408 | 0.83 | DRD4 (0.51) | ALDH1A1SMN1; SMN2KMT2AALOX15CA1 | |
| SCHEMBL9988387 | 0.82 | DRD4 (0.49) | SMN1; SMN2ALOX15CA1CA2CA9 | |
| SCHEMBL9989142 | 0.78 | CA1 (0.48) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9988456 | 0.77 | SLC16A3 (0.53) | SMN1; SMN2RAB9ARCE1LMNACA1 | |
| SCHEMBL9988869 | 0.77 | KDM4E (0.49) | ALDH1A1KMT2ACA1CA2CA9 | |
| SCHEMBL9988915 | 0.77 | CA1 (0.47) | ALDH1A1CA1CA2CA9KDM4E | |
| SCHEMBL9988576 | 0.77 | LMNA (0.47) | ALDH1A1SMN1; SMN2LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |